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Test Code: F8I Preferred Name Factor VIII inhibitor

No
24 hours
As required
N/A
Medicare Item
2 hours

Test Tubes

ImageSpecimen TypeSpecimen VolumeTube Type
Blood (adult)8.1ml4 x Sodium Citrate 2.7ml (Solid Pale Blue Top)
Blood (paediatric)2.7 mLSodium Citrate

COLLECTION NOTES

Accurate filling of specimen tube essential.
Specimens must be transported at room temperature to the Laboratory in a red specimen bag  ASAP. (Maximum delay to laboratory must not exceed 2hrs)

Minimum collection of 8 mL recommended - if difficulty collecting this amount please contact laboratory

GENERAL NOTES



F VIII inhibitors may develop in patients with severe Haemophilia A as a complication of therapy OR in patients with autoimmune disorders, malignancies, or no apparent previous disorder. In haemophilia A, the inhibitor/F VIII complex (antibody/antigen complex) has no factor activity, while in patients with acquired factor deficiencies due to inhibitors, some F VIII activity is shown. [Anti-von Willebrand autoantibodies with resulting F VIII deficiency have been described in patients with multiple myeloma.]

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