Test Code: F5 Preferred Name Factor V

2 hours
1 week
Medicare Item
2 hours

Test Tubes

ImageSpecimen TypeSpecimen VolumeTube Type
Blood (adult)2.7 mLSodium Citrate 2.7 mL (Solid Pale Blue Top)
Blood (paediatric)1.8 mLSodium Citrate 1.8 mL Paed (Clear/Pale Blue Inner)
Blood (neonate)1.0 mLSodium Citrate 1.0 mL Neonate (Pale Blue Top)


Accurate filling of specimen tube essential.
Specimens must be transported at room temperature to the Laboratory in a red specimen bag ASAP. (Maximum delay to testing laboratory must not exceed 2hrs)
* If several factor assays are requested e.g. II, V,VII and X, a total of 3 x sodium citrate tubes are required for an adult and 2 tubes for a child.


Factor V has a biological half-life of 36 hours. Acquired F V deficiency is seen with chronic liver disease and is a better predictor of overall synthetic liver impairment than deficiency of the Vit K-dependant factors. There are no available factor V concentrates.  Fresh frozen plasma (FFP) is the only treatment available for F V deficiency.  In acute cases of severe bleeding, the addition of platelet concentrates may be helpful.  Depending upon availability, solvent-detergent FFP may contain a more reliable level of Factor V than standard FFP. Paradoxically, several reports exist of patients with congenital F V deficiency that present with thrombosis!

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