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Test Code: F5 Preferred Name Factor V

No
2 hours
Weekly
1 week
Medicare Item
2 hours

Test Tubes

ImageSpecimen TypeSpecimen VolumeTube Type
Blood (adult)2.7 mLSodium Citrate 2.7 mL (Solid Pale Blue Top)
Blood (paediatric)1.8 mLSodium Citrate 1.8 mL Paed (Clear/Pale Blue Inner)
Blood (neonate)1.0 mLSodium Citrate 1.0 mL Neonate (Pale Blue Top)

COLLECTION NOTES

Accurate filling of specimen tube essential.
Specimens must be transported at room temperature to the Laboratory in a red specimen bag ASAP. (Maximum delay to testing laboratory must not exceed 2hrs)
* If several factor assays are requested e.g. II, V,VII and X, a total of 3 x sodium citrate tubes are required for an adult and 2 tubes for a child.

GENERAL NOTES



Factor V has a biological half-life of 36 hours. Acquired F V deficiency is seen with chronic liver disease and is a better predictor of overall synthetic liver impairment than deficiency of the Vit K-dependant factors. There are no available factor V concentrates.  Fresh frozen plasma (FFP) is the only treatment available for F V deficiency.  In acute cases of severe bleeding, the addition of platelet concentrates may be helpful.  Depending upon availability, solvent-detergent FFP may contain a more reliable level of Factor V than standard FFP. Paradoxically, several reports exist of patients with congenital F V deficiency that present with thrombosis!

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