Sodium Citrate 1.8 mL Paed (Clear/Pale Blue Inner)
Sodium Citrate 1.0 mL Neonate (Pale Blue Top)
Accurate filling of specimen tube essential. Specimens must be transported at room temperature to the Laboratory in a red specimen bag ASAP. (Maximum delay to testing laboratory must not exceed 2hrs) * If several factor assays are requested e.g. II, V,VII and X, a total of 3 x sodium citrate tubes are required for an adult and 2 tubes for a child.
Factor V has a biological half-life of 36 hours. Acquired F V deficiency is seen with chronic liver disease and is a better predictor of overall synthetic liver impairment than deficiency of the Vit K-dependant factors. There are no available factor V concentrates. Fresh frozen plasma (FFP) is the only treatment available for F V deficiency. In acute cases of severe bleeding, the addition of platelet concentrates may be helpful. Depending upon availability, solvent-detergent FFP may contain a more reliable level of Factor V than standard FFP. Paradoxically, several reports exist of patients with congenital F V deficiency that present with thrombosis!