Test Code: F2 Preferred Name Factor II

2 hours
1 week
Medicare Item
2 hours

Test Tubes

ImageSpecimen TypeSpecimen VolumeTube Type
Blood (adult)2.7 mLSodium Citrate 2.7 mL (Solid Pale Blue Top)
Blood (paediatric)1.8 mLSodium Citrate 1.8 mL Paed (Clear/Pale Blue Inner)
Blood (neonate)1.0 mLSodium Citrate 1.0 mL Neonate (Pale Blue Top)


Accurate filling of specimen tube essential.
Specimens must be transported at room temperature to the Laboratory in a red specimen bag ASAP. (Maximum delay to testing laboratory must not exceed 2hrs)
* If several factor assays are requested e.g. II, V,VII and X, a total of 3 x sodium citrate tubes are required for an adult and 2 tubes for a child.


Prothrombin has a biological half-life of 3 days. Fewer than 100 cases of prothrombin deficiency have been described. Acquired F II deficiency may be due to liver disease and Vit K deficiency/antagonism. Antibodies against F II can be seen in patients with the lupus anticoagulant or the antiphospholipid syndrome and on rare occasions as isolated cases.

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