Test Code: LD Preferred Name Lactate dehydrogenase

60 minutes
All hours
4 hours
Medicare Item

Test Tubes

ImageSpecimen TypeSpecimen VolumeTube Type
Blood (adult)5 mLSST 5 mL (Biochem) with GEL (Dark Yellow Top)
Blood (paediatric)1 mL2x SST with gel 600 uL Paed (Red or Yellow top)
Blood (neonatal)500 µLSST with gel 600 uL Paed (Red or Yellow top)


Avoid haemolysis.


APPLICATION:  Superseded by Troponin I in the diagnosis of myocardial infarction when testing is required >48 hours after the onset of chest pain.  It is occasionally useful in the assessment of patients with liver disease or malignancy (especially lymphoma, seminoma, hepatic matastases); anaemia when haemolysis or ineffective erythropoiesis suspected.  Although it may be elevated in patients with skeletal muscle damage, it is not a useful or diagnostic test in this situation.

INTERPRETATION:  The ubiquitous tissue distribution of LD makes it a non-specific indicator of disease.  Increased levels are found in myocardial infarction, liver disease, haemolysis, ineffective erythropoiesis, some malignancies (especially non-Hodgkins lympyoma) and numerous other disease processes involving tissue damage.  Haemolysis during collection, delays in processing, or refrigeration of unseparated blood may cause an artefactual increase in enzyme activity.

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