APPLICATION: Diagnosis of acromegaly or gigantism. Diagnosis of Laron dwarfism. Assessment of growth hormone deficiency or nutritional status.
INTERPRETATION: Levels are increased in acromegaly, and the test is used in the initial assessment of patients, prior to a growth hormone suppression test. Its diagnostic value is limited at the time of puberty and in malnutrition and severe illness. In Laron dwarfism, a rare disease, growth hormone is not reduced but IGF-1 is reduced.