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Test Code: PlatEM Preferred Name Platelet electron microscopy

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Medicare Item
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Test Tubes

ImageSpecimen TypeSpecimen VolumeTube Type
whole blood2x Sodium Citrate 2.7 ml (Solid Pale Blue Top)
whole bloodSodium Citrate 1.8 mL Paed (Clear/Pale Blue Inner)

COLLECTION NOTES

Do not collect without approval from PQ-RBH testing scientist.
The test needs to be booked in to Pathology Queensland.
Testing is ONLY Monday - Wednesday: sample must be received by noon.

Transport to RBH to be arranged with CSR.

Adult - 2 x 2.7mL citrate tubes
Paediatric 2-3 x 1.8mL citrate tubes

(RBH anatomical pathology contact Naomi McCallum 3646 8057)

GENERAL NOTES



The electron microscope is a sophisticated instrument that can be used for the clinical diagnosis of inherited platelet disorders. Instances in which electron microscopy has been critical for identifying and characterizing genetic problems include platelet storage pool deficiency (SPD) which is due to a marked decrease or absence of the organelles storing adenine nucleotides, serotonin, and calcium destined for secretion during the platelet release reaction. The organelles are referred to as dense bodies because they are inherently electron opaque. As a result, platelet SPD is more rapidly and reliably diagnosed in the electron microscope than by any other technique. Giant platelet disorders have presented a bewildering array. The electron microscope has made it possible to separate the various types into distinct conditions based on the nature of platelet structural defects and inclusions found in leukocytes.

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