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Test Code: Echis Preferred Name Echis

Yes
1 hour
As required
4 hours
Medicare Item

Test Tubes

ImageSpecimen TypeSpecimen VolumeTube Type
Blood (adult)2.7mlSodium Citrate 2.7 mL (Solid Pale Blue Top)
Blood (paediatric)1.8mlSodium Citrate 1.8 mL Paed (Clear/Pale Blue Inner)
Blood (neonate)1.0Sodium Citrate 1.0 mL Neonate (Pale Blue Top)

COLLECTION NOTES

Accurate filling of specimen tube essential.    
All collections that include Coagulation testing must be sent to the laboratory in a BLUE specimen bag.
Please ask the patient what anticoagulants they are on and the dose, record on request form.

GENERAL NOTES



The ECHIS test is used to differentiate liver disease from Vit K deficiency/Vit K antagonism as a possible cause of a prolonged PT. Both active and inactive Vit K-dependent factors are decreased in liver disease, resulting in a prolonged PT AND prolonged ECHIS time. Vit K deficiency/antagonism results in a reduced ACTIVE form but the INACTIVE form is normal or increased; PT is prolonged but ECHIS time is normal. [ECHIS venom activates both the functionally inactive and the carboxylated active F II (prothrombin) to thrombin.]

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