APPLICATION: Provides a useful indicator of prognosis and can be used to follow progression in multiple myeloma. Prediction of prognosis in HIV infection, in association with absolute CD4 count and viral load.
INTERPRETATION: Levels are correlated with tumour load, and thus prognosis, in multiple myeloma. A beta-2-microglobulin level of >4.0 mg/L is associated with increased progression to AIDS.